Committee Meetings

2010 Program Committee
(second meeting)

Web Site Committee

Symposium 14
Chemical and Radiation Induced Persistent and Untargeted Genetic Instability

Ionizing Radiation Induces Microhomology-Mediated End-Joining In Trans in Yeast and Mammalian Cells
Speaker: Robert H. Schiestl, UCLA School of Medicine and Public Health

Mechanisms of Long Term Accumulation of Mutations: Clonal Expansion and Epigenetic Changes
Speaker: Bevin P. Engelward, Massachusetts Institute of Technology

Germ Cells Mediate Untargeted Mutagenesis in the Maternal
Genome of Progeny
Speaker: Richard N. Winn, University of Georgia

Radiation-Induced Persistent Genomic Instability
Speaker: Charles L. Limoli, University of California, Irvine

Symposium 15
Women in Environmental Mutagen Society Special Interest Group Women’s Health Issues: Diagnosis and Treatment in the 21^st Century

Contributing Sponsors: National Institute of Environmental Health Sciences, NIH and Office of Research in Women's Health, NIH

Challenges of Epidemiologic Research in the Genomic Era:  The Example of Ovarian Cancer
Speaker: Patricia G. Moorman, Duke University

Novel Epigenetic Biomarkers for Early Detection of Breast Cancer
and Prediction of Treatment Responses: from Bench to Bedside
Speaker: Olga Kovalchuk, University of Lethbridge

Obesity, Vitamin Supplementation and Biomarkers of Oxidative Stress and Cardiovascular Disease
Speaker: Nina T. Holland, University of California, Berkeley

PALB2 Physically and Functionally Connects BRCA1 and BRCA2 into a Pathway of Homologous Recombination
Zhang F, Fan Q, Ren K, Andreassen PR. Cincinnati Children's Research Foundation, Cincinnati, OH, United States

Plenary Lecture 5
Mending Human Genes
EMS Award Recpient

Lecturer: James E. Cleaver, University of California, San Francisco

Lunch on Own

Town Hall Meeting

EMS Strategic Plan and Implementation

Platform Session 3
Risk/Regulation

Platform presenter designated by underlined author.

Chairperson: Richard D. Wood, The University of Texas MD Anderson Cancer Center

Accelerated Tumorigenesis in the Absence of DNA Polymerase Zeta
Wittschieben JP, Patil V, Glushets V, Robinson LJ, Wood RD

CYPD6*16 Testing to Accurately Detect Poor Metabolizers
Phillips SL, Clark LS

Polyploidy-Induction by Dihydroxylated Monochloro-Biphenyls and Structure-Activity-Relationship?
Flor S, Ludewig G

Spectrum of Chromosomal Aneuploidy, Benzene Exposure and Leukemia Risk
Zhang L, Lan Q, Guo W, Hubbard A, Li G, Rappaport SM, Ji Z, Shen M, Vermeulen R, Yin S, Rothman N, Smith MT

Genotoxicity Evaluation of Hepatocarcinogens in Rat Liver Tissue by Systems Toxicology Approach
Chung Y-S, Yum YN, Kim JE, Koo KH, Lee WS, Park SN

Germline Mutation in Mice Exposed to Mainstream and Sidestream Tobacco Smoke
Marchetti F, Rowan-Carroll A, Berndt-Weis ML, Polyzos A, Yauk C

Molecular and Genetic Factors Influence on DNA Repair Efficiency and Health Hazard
Cebulska-Wasilewska A

Human Risk by the Environmental Exposure to Benzo[a]pyrene
Sram RJ, Binkova B, Beskid O, Milcova A, Rossner P, Rossnerova A, Solansky I, Topinka J

Platform Session 4
Genetic Toxicology/Environmental Mutagenesis

Platform presenter designated by underlined author.

Chairpersons: Robert H. Heflich, National Center for Toxicological Research, U.S. FDA and Helena Groot de Restrepo, Universidad de los Andes

Comparative DNA Damage and Repair Kinetics Study in Mammalian Cells by Chloro-, Bromo-, and Iodoacetic Acid
Komaki Y, Pals J, Wagner E, Marinas B, Plewa MJ

The Somatic Microindels in Human Cancer Are Highly Error-Prone and Suggest the Involvement of an As Yet Uncharacterized Repair Pathway
Sommer S, Gonzalez K, Scaringe W

Elucidating the Functional Consequences of the Trichloroethylene Associated Von-Hippel Lindau Tumor Suppressor Gene Mutation Using a Genetically Engineered Model System
DeSimone MC, Rathmell WK, Threadgill DW

European Hot Spot of Air Pollution by PM2.5 and B[a]P: Ostrava, Czech Republic
Sram RJ, Milcova A, Pastorkova A, Rossner, Jr. P, Rossnerova A, Solansky I, Svecova V, Topinka J

GADD45a-GFP Test Results from ECVAM Recommended Lists of Compounds for the Assessment of New or Improved Genotoxicity Tests
Walmsley RM, Tate M, Cahill P, Birrell L, Hughes C, Jagger C, Knight A, Billinton N

Detecting PIG-A Gene Mutation in Human Red Blood Cells
Dobrovolsky VN, Bigger CAH, Elespuru RK, Robison TW, Heflich RH

Occupational Exposure to Organic Solvents: Biomarkers of Exposure, Effect and Susceptibility
Varona M, Torres CH, Diaz S, Patiño RI, Albores A, Narvaez DM, Groot H

Future Application of Genetic Toxicity Assays
Elespuru RK, Agarwal R, Atrakchi A, Bigger CAH, Heflich RH, Jagannath DR, Levy DD, Moore MM, Ouyang Y, Robison TW, Cimino MC, Dearfield KL

Symposium 16
Nanotechnology: An Insight on the Toxicology of Nanoparticles

Regulatory Issues Surrounding Nanoparticles
Speaker: Penelope Rice, CFSA, U.S. Food and Drug Administration

Overview on the Genotoxicity of Nanoparticles
Speaker: Micheline Kirsch-Volders, Vrije Universiteit Brussels

Issues Surrounding the Testing of Nanoparticles for Genotoxicity
Speaker: Fanqing Frank Chen, Lawrence Berkeley National Laboratory

Aneugenic and Clastogenic Effects of Amorphous Silica Nanoparticles in A549 Human Lung Carcinoma Cells: Size Matters?
Gonzalez L¹, Thomassen L², Plas G¹, Rabolli V³, Napierska D², Decordier I¹, Hoet P², Martens J², Lison D³, Kirsch-Volders M¹. ¹Vrije Universiteit Brussel, Brussels, Belgium, ²Katholieke Universiteit Leuven, Leuven, Belgium, ³Université Catholique de Louvain, Brussels, Belgium

Symposium 17
Use of DNA Adduct Data in Risk Assessment: Context is Everything!

Contributing Sponsors: American Chemical Council Ethylene Oxide Panel Toxicology Research Task Group, American Chemical Council Olefins Panel Ethylene/Propylene Work Group (Olefins Panel E/PWG), and ILSI-HESI DNA Adducts Project Committee

Overview/Objectives of ILSI-HESI DNA Adduct Project Committee
Speaker: Lynn H. Pottenger, The Dow Chemical Company

Creating Context for the Use of DNA Adduct Data in Risk Assessment
Speaker: Rita Schoeny, U.S. Environmental Protection Agency

DNA Adduct Measurements: Promise and Pitfalls
Speaker: Matthew W. Himmelstein, DuPont Haskell Global Center for
Health and Environmental Sciences

Biomarkers of Exposure and Effect: Implications for Risk Assessment
Speaker: James A. Swenberg, University of North Carolina

Case Study Examples
Speaker: Elizabeth Martin, AstraZeneca

Regulatory Views on Use of DNA Adduct Data in Risk Assessment
Speaker: Rita Schoeny, U.S. Environmental Protection Agency

EMS Council Meeting